| 摘要 |
NEW MATERIAL:Antibiotic R106 shown by the formula (MeVal is N- methylvaline; NePhe is N-methylphenylalanine; beta-HOMeVal is beta-hydroxy-N- methylvaline) having the following physical and chemical properties. Elemental analysis (%): C 65.0, H 8.5 N 9.9. Melting point: 138-140 deg.C. Specific rotatory power: [alpha] =- 2554.3 (C=1.0 methanol). Molecular weight: FAB-MS m/Z 1,101 (N+H), 1123 (M+Na). Color reaction: positive in 50% sulfuric acid and KMnO4 and negative in ninhydrin and FeCl3. Solubility: soluble in chloroform, methanol, ethanol, DMF and dimethyl sulfoxide and slightly soluble in water. Color: white. Neutral substance, etc. USE:An antimicrobial agent. PREPARATION:A strain of Aureobasidium NoR106 (FERM BP-1938) is cultured. |
