发明名称 |
3.BETA.,17.BETA.-HYDROXY-SUBSTITUTED STEROIDS AND RELATED STEROIDAL COMPOUNDS |
摘要 |
The present invention is directed to a group of compounds which are 3.beta.,17.beta.-hydroxy steroids, and related steroidal structures. These compounds are aromatase inhibitors, and thus, regulate or inhibit the conversion of androgens to estrogens. These compounds may be utilized to treat conditions potentiated by the presence of estrogens. These compounds exhibit a slower onset of action and a longer half life relative to the 10-(2-alkynyl) steroidal aromatase inhibitors disclosed in U.S. Patent 4,322,416.
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申请公布号 |
CA2001264(A1) |
申请公布日期 |
1990.04.27 |
申请号 |
CA19892001264 |
申请日期 |
1989.10.23 |
申请人 |
MERRELL DOW PHARMACEUTICALS (CANADA) INC. |
发明人 |
JOHNSTON, JOHN O.;HOLBERT, GENE W. |
分类号 |
A61K31/565;A61P43/00;C07J1/00;(IPC1-7):C07J1/00 |
主分类号 |
A61K31/565 |
代理机构 |
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主权项 |
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地址 |
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