METHOD FOR OBTAINING 4-PHENYL-2-PYRROLIDONE-ACETIC-1 ACID AMIDE.

摘要

A method of obtaining 4-phenyl-2-pyrrolidone-acetic-1 acid amide consists in reacting the 4-phenyl-2-pyrrolidone with an excess of alkali in the medium of an aprotic solvent at a temperature of 70-130 DEG C. The obtained N-substituted derivative of 4-phenyl-2-pyrrolidone is then reacted with an ether of halogeno-acetic acid and the thus obtained product is then reacted with aqua-ammonia and the desired product is extracted. The obtained amide of 4-phenyl-2-pyrrolidone-acetic-1 acid has an anticonvulsive activity.