.beta.-D-GALACTOSE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE

摘要

HOE 82/B 010 of the disclosure: New compounds of the general formula I I in which R1 and R2 each denote a hydrogen atom or an acyl or benzyl protective group, R1 and R2 together denote an alkylidene or benzylidene protective group, R4 denotes a hydrogen atom, an acyl or benzyl protective group or a 2,3,4-tri-0-benzyl-?-L-fucopyranosyl or ?-L-fucopyranosyl radical, R5 denotes H, OH, NH2, NHNH2, N3, O-alkyl, O-aryl, NH-(CH2)mMH2, where m = 2 - 5, lysine, polylysine or a carrier, n denotes a number from 1 to 10 and R3 denotes a hydrogen atom, an acyl or benzyl protective group or an ?-D-glycopyranosyl radical of the general formula II II in which R6 denotes a hydrogen atom or an acyl or benzyl protective group, R7 denotes a hydrogen atom or halogen and R8 denotes a hydrogen atom, an acyloxy or benzyloxy group or an azido, amino, acetamido or hydroxyl group, a process for their preparation and their use, when bonded to a carrier, as synthetic antigens, glycolipids or immuno-adsorbents, are described.