发明名称 |
19-fluoro- or cyano- 21-hydroxyprogesterone derivatives useful as 19-hydroxylase inhibitors. |
摘要 |
<p>19-Fluoro- and cyano- substituted 21-hydroxyprogesterone derivatives and related compounds which are active as 19-hydroxylase inhibitors and useful as antihypertensive agents are described herein. The compounds are prepared using appropriate synthetic pathways which will vary according to the nature of the specific 19-substituted progesterone or related compound desired.</p> |
申请公布号 |
EP0348911(A2) |
申请公布日期 |
1990.01.03 |
申请号 |
EP19890111699 |
申请日期 |
1989.06.27 |
申请人 |
MERRELL DOW PHARMACEUTICALS INC. |
发明人 |
HOLBERT, GENE W.;JOHNSTON, J. O'NEAL |
分类号 |
C12N9/99;A61K31/57;A61P9/12;A61P43/00;C07J5/00;C07J13/00;C07J21/00;C07J41/00 |
主分类号 |
C12N9/99 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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