发明名称 |
COMPOSITIONS FOR THE PREPARATION OF MICROPARTICLES BY EXTRUSION FOR THE SUSTAINED RELEASE OF BIOLOGICALLY ACTIVE SUBSTANCES, AND MICROPARTICLES SO OBTAINED |
摘要 |
1. A composition for the preparation by extrusion of microparticles permitting a prolonged release of a biologically active substance, which composition consists of a biologically active substance, one or more non-hydrophilic polymers and from 10 to 40% by weight either of a mixture of at least two lipid excipients one of which has the property of dissolving or gelling the polymer or polymers and the other has lubricating properties or of a lipid excipient having both the property of dissolving or gelling the polymer or polymers and lubricating properties, and, if appropriate, one or more additives chosen from diluents and antistatic agents. |
申请公布号 |
DE3664867(D1) |
申请公布日期 |
1989.09.14 |
申请号 |
DE19863664867 |
申请日期 |
1986.05.09 |
申请人 |
RHONE-POULENC SANTE |
发明人 |
DROUIN, JEHAN-YVES;VEILLARD, MICHEL |
分类号 |
A61K47/44;A61K9/16;A61K9/22;A61K47/30;(IPC1-7):A61K9/22;A61K9/52 |
主分类号 |
A61K47/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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