Chimeric antibodies directed against human carcinoembryonic antigen.

摘要

The present invention discloses novel chimeric monoclonal antibodies, directed against human carcinoembryonic antigen, having antigen-specific variable regions of defined amino acid sequences. DNA constructs for the light and heavy chain variable regions comprising the novel antibodies of the invention are provided. Eukaryotic host cells capable of expression of the chimeric antibodies and comprising the novel chimeric antibody-encoding DNA constructs are also provided.