摘要 |
<p>Mucin coated Sepharose is used as a laboratory model to measure the affinity of a postulated lipid composition in liposome configuration for binding to mucin. The preferred lipid composition provides a first lipid moiety which projects a positive charged ion. A second lipid moiety enhances the positive charge by neutralizing all intermediate negative charges of the first lipid. The result is a liposome with strong positive charge areas which will bind to mucin.</p> |