发明名称 |
Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them. |
摘要 |
<p>Novel compounds of formula (I), processes for their preparation, and their use as pharmaceutical agents are described: <CHEM> in which p represents an integer of 2 to 4; r represents an integer of 1 or 2; s represents 0 or 1; and X represents a group <CHEM> in which A1 is oxygen or sulphur, one of A2 and A3 is CR1 and the other is nitrogen or CR2, or A2 is oxygen or sulphur, A1 is CH and A3 is CR1, where R1 and R2 are independently selected from hydrogen and C1-2 alkyl, with the proviso that when r is 2, R1 and R2 are hydrogen or methyl.</p> |
申请公布号 |
EP0322182(A2) |
申请公布日期 |
1989.06.28 |
申请号 |
EP19880312038 |
申请日期 |
1988.12.19 |
申请人 |
BEECHAM GROUP PLC |
发明人 |
ORLEK, BARRY SIDNEY BEECHAM PHARMACEUTICALS;WYMAN, PAUL ADRIAN BEECHAM PHARMACEUTICALS;WADSWORTH, HARRY JOHN BEECHAM PHARMACEUTICALS |
分类号 |
A61K31/395;A61K31/435;A61K31/55;A61P25/02;C07D453/02;C07D471/08;C07D487/08 |
主分类号 |
A61K31/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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