COMPOSITIONS AND METHODS OF ENHANCING TRANSDERMAL AND TRANSMEMBRANE PENETRATION OF TOPICAL AND SYSTEMIC AGENTS

摘要

COMPOSITIONS AND METHODS OF ENHANCING TRANSDERMAL AND TRANSMEMBRANE PENETRATION OF TOPICAL AND SYSTEMIC AGENTS Compositions and methods useful for enhancing the transdermal and transmembrane drug delivery of topical and systemic agents. The compositions and methods comprise the active agent together with an effective amount of certain amides of heterocyclic amines as defined herein as penetration enhancers and topically administering to human or animal skin or other membranes the resulting compositions.