发明名称 |
NEW BENZAMIDES AS PRARγ MODULATORS |
摘要 |
Compounds of general structure (I), wherein the central benzene ring may be substituted in the meta- or para-position; -A is an optionally substituted hydroxyl, alkoxyl, hydroxylamine, alkoxylamine or amine radical; -W is an N- and C-linked biradical selected from several possibilities; and -Z is a carbon radical selected from several possibilities. These compounds are PPARγ and PPARγ/PPARδ modulators and, therefore, are useful for the prophylactic and/or curative treatment of a condition or a disease mediated by these receptors. |
申请公布号 |
EA008798(B1) |
申请公布日期 |
2007.08.31 |
申请号 |
EA20060000023 |
申请日期 |
2004.06.11 |
申请人 |
LABORATORIOS S.A.L.V.A.T., S.A. |
发明人 |
FERNANDEZ SERRAT, ANNA;SERRA COMAS CARME;BALSA LOPEZ DOLORS;LLEBARIA SOLDEVILA AMADEU;FARRERONS GALLEMI CARLES;MIQUEL BONO IGNACIO, JOSE;CATENARUIZ JUAN, LORENZO;LAGUNAS ARNAL CARMEN;CORDOMI MONTOYA ARNAU;SALCEDO ROCA CAROLINA;TOLEDO MESA NATIVIDAD;MARRERO GONSALEZ PEDRO;HARO BAUTISTA DIEGO;FERNANDEZ GARCIA ANDRES |
分类号 |
C07C235/52;A61K31/166;A61K31/381;A61K31/404;A61K31/435;A61K31/498;A61P5/00;C07D209/04;C07D209/18;C07D213/02;C07D213/30;C07D215/20;C07D215/22;C07D215/227;C07D215/26;C07D223/16;C07D233/54;C07D241/40;C07D241/44;C07D277/64;C07D333/08;C07D333/16 |
主分类号 |
C07C235/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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