发明名称 |
4-HYDROXYMETHYL-PYRROLIDINONES SUBSTITUTED IN THE ONE POSITION, PROCESSES FOR PREPARING THEM, PHARMACEUTICAL COMPOSITIONS AND INTERMEDIATE PRODUCTS FOR PREPARING THEM, PHARMACEUTICAL COMPOSITIONS AND INTERMEDIATE PRODUCTS |
摘要 |
<p>Pyrrolidinone derivatives, process for their preparation and pharmaceutical compositions containing them The invention relates to a compound of formula I (I) wherein R1 represents a hydrogen atom or an alkyl group of 1 to 4 carbon atoms and R2 represents a phenyl group optionally monodi- or tri-substituted by an alkyl group of 1 to 2 carbon atoms, an alkoxy group of 1 to 2 carbon atoms, a fluorine, chlorine or bromine atom or a trifluoromethyl, nitro, benzyloxy or hydroxy group; or a pyridyl group. Processes for the preparation of the new compounds are also described. In animal trials the new compounds have proved effective in alleviating or remedying conditions of restricted cerebral performance.</p> |
申请公布号 |
CA1253159(A) |
申请公布日期 |
1989.04.25 |
申请号 |
CA19840459535 |
申请日期 |
1984.07.24 |
申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL G.M.B.H. |
发明人 |
WEBER, KARL-HEINZ;WALTHER, GERHARD;SCHNEIDER, CLAUS;HINZEN, DIETER;KUHN, FRANZ J.;LEHR, ERICH |
分类号 |
C07D205/08;A61K31/397;A61K31/40;A61K31/4015;A61K31/44;A61K31/4427;A61P25/28;C07D207/26;C07D207/27;C07D207/277;C07D401/06;(IPC1-7):C07D207/26 |
主分类号 |
C07D205/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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