发明名称 DERIVES DE PROPIOLOPHENONE
摘要 Propiolophenone derivatives of the formula <IMAGE> I wherein R6 is hydrogen, lower alkyl or a group of the formula COOR7, (a) CONR8R9, (b) C(R10)O, (c) C(R11)(OR12)2, (d) C(OR13)3 (e) or C(R14)(R15)OR16; (f) as well as corresponding hydroxy compounds of the formula <IMAGE> II wherein R6' is hydrogen, lower alkyl, a group of formula (a), (b), (c), (d) or (e) or a group of the formula -C(R14)(R15)OR16'(f'): exhibit mucosa-protective and/or gastric acid secretion-inhibiting properties, such that they can be used for the control or prevention of illnesses of the gastrointestinal tract, especially against gastric ulcers and/or duodenal ulcers.
申请公布号 MC1916(A) 申请公布日期 1989.04.06
申请号 MC19880001960 申请日期 1988.03.17
申请人 F. HOFFMANN-LA ROCHE 发明人 ALBERT FISCHLI;EVA-MARIA GUTKNECHT;DANIEL OBRECHT
分类号 C07C45/29;C07C45/45;C07C45/51;C07C45/67;C07C49/794;C07C49/796;C07C49/813;C07C49/835;C07C49/84;C07C49/86;C07C59/66;C07C59/68;C07C323/22;C07D317/54;C07D317/60;C07F7/18;(IPC1-7):C07C/;C07D/;A61K/ 主分类号 C07C45/29
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