ANTIPHLOGISTIKA ENTHALTENDE THERMOPLASTISCHE KUNSTSTOFFE.

摘要

1. Thermoplastics containing antiinflammatory agents for cannulas, catheters, tubes, artificial blood vessels, implants, heart valves and films, which can be produced from thermoplastics from the group comprising polyolefines, styrene polymers, polyvinyl halides, polycarbonates, polyesters, polyamides, polyphenylene oxides, polyacetals, cellulose esters or polyurethanes and copolymers of the abovementioned polymers and antiinflammatory agents of the formula see diagramm : EP0132690,P13,F1 wherein R**1 to R**5 represent hydrogen, halogen, lower alkyl or substituted alkyl, X represents N or CH and Y represents hydrogen, metal ions, alkyl or substituted alkyl, and/or of the formula see diagramm : EP0132690,P13,F2 wherein R represents hydrogen, lower alkyl or substituted alkyl, Ar represents aryl, heteroaryl, substituted aryl or substituted heteroaryl and n + m denote an integer and have the value zero, 1 or 2 and p denotes zero or 1, with the proviso that Ar does not denote aryl or heteroaryl if m + n and p have the value zero, and esters or amides thereof, and/or of the formula see diagramm : EP0132690,P13,F3 wherein R**6 and R**7 together form an aryl or heteroaryl ring with an N atom, R**8 represents a lower alkyl group with 1-4 C atoms and R**9 represents a heteroaryl radical with at least one heteroatom, wherein the components have been mixed in an extruder and then homogenized, in a temperature range at which the thermoplastic plasticizes and the antiinflammatory agent is in liquid form.