发明名称 |
ANTENATAL SCREENING FOR DOWN'S SYNDROME |
摘要 |
An antenatal screening test for risk of Down's Syndrome in a foetus, which is carried out on a maternal blood sample before the beginning of the third trimester of pregnancy, comprises assaying the sample for a metabolite of feto-placental activity which is affected by the presence of Down's Syndrome, and which may be selected from unconjugated oestriol; progesterone; 16-alpha-hydroxy-dehydroepiandrosterone sulphate (16-alpha-hydroxy-DHEAS); and, dehydroepiandrosterone sulphate (DHEAS). The method may also include an additional assay for alpha-fetoprotein and/or human chorionic gonadotrophin. |
申请公布号 |
WO8900696(A1) |
申请公布日期 |
1989.01.26 |
申请号 |
WO1988GB00557 |
申请日期 |
1988.07.11 |
申请人 |
RESEARCH CORPORATION LIMITED |
发明人 |
WALD, NICHOLAS, JOHN;CUCKLE, HOWARD, STEPHEN;CANICK, JACOB, ABRAHAM;HADDOW, JAMES, EDWARD |
分类号 |
G01N33/50;G01N33/68;G01N33/74;G01N33/76;(IPC1-7):G01N33/74 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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