发明名称 |
Solubilisation and oxidation of somatotropin from transformed microorganisms. |
摘要 |
<p>This invention discloses a commercially advantageous process for extraction and purification of protein from microorganisms. The initial steps of the process are useful for purifying many insoluble proteins while later steps are designed to renature denatured somatotropins produced by transformed microorganisms. The process is especially useful for purifying recombinantly-produced bovine somatotropin.</p> |
申请公布号 |
EP0263902(A1) |
申请公布日期 |
1988.04.20 |
申请号 |
EP19860307769 |
申请日期 |
1986.10.08 |
申请人 |
THE UPJOHN COMPANY |
发明人 |
EVANS, TIMOTHY W.;KNUTH, MARK W. |
分类号 |
C07K1/113;C07K14/00;C07K14/575;C07K14/61;C07K19/00;C12N15/00;C12N15/09;C12R1/19;C12P21/02;C07K1/107;(IPC1-7):C12P21/02;C07K3/08;C12N1/06 |
主分类号 |
C07K1/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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