| 摘要 |
A method for enhancing growth of fine vellous hair into terminal hair in an at least partially bald person which comprises topically applying to the scalp a compound selected from the group consisting of 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6-chloro-3-(dichloromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-su lfonamide 1,1-dioxide, 2-chloro-5-(1-hydroxy-3-oxo-1-isoindolinyl)benzene sulfonamide, 3,4-dihydro-3-(phenylmethyl)-6-(trifluoromethyl)-2H-1,2,4-benzothiadia zine-7-sulfonamide 1,1-dioxide, 6-chloro-3-(chloromethyl)-3,4-dihydro-2-methyl-2H-1,2,4-benzothiadiazi ne-7-sulfonamide 1,1-dioxide, 6-chloro-3,4-dihydro-2-methyl-3-{[(2,2,2-trifluoroethyl)thio]methyl}-2 H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide and 6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide whereby the smooth muscles in the small blood vessels in the papilla part of connective tissue of skin that supplies the hair follicle is relaxed, thereby increasing blood flow to the hair matrix leading to the maturation of fine hairs into terminal hairs. Also provided is a topical medication and method for reversing the effects of baldness focused upon said compound as the active ingredient. A kit is provided which comprises the medication with said compound suitable for reversing the effects of baldness on the scalp of an at least partially bald subject which comprises a package including said compound and directions for administration of said compound to said scalp for the reversal of the effects of baldness. |
