Steroids for use as immunomodulators

摘要

The invention relates to a group of DELTA 4- and DELTA 5(10)-oestrene derivatives having an alkyl(1-4 C) substituent in position 6 or 7, an oxy substituent in position 17 beta and optionally an oxo- or oxy-substituent in position 3 and a hydrocarbyl(1-4 C) group in position 17 alpha , for use as immunomodulator. The compounds are in particular suitable for therapeutic use in the treatment of auto-immune diseases.