Lipoxygenase and cyclogenase inhibiting thiachromen and thiepan derivatives and pharmaceutical compositions therefor

摘要

This invention relates to bicyclic catechol derivatives having the general formulae I and II <IMAGE> I <IMAGE> II wherein R1, R2, R3 and Z represent various substituents, to a preparation process of the same comprising reacting a compound of formula III <IMAGE> III wherein R1 and R2 have the meanings given above with an appropriately substituted propionic or butyric acid (or an ester or a salt of the same) of formula IV <IMAGE> IV wherein R3 has the meaning given above, and to therapeutical compositions wherein the active ingredient is one of these compounds.