| 摘要 |
<p>A method for preparing an unprotected hydroxy compound from a protected hydroxy compound of the general formula I <CHEM> in which R1 is the non-hydroxy moiety of the protected hydroxy compound; R2, R3, R4 and R5 which may be the same or different are hydrogen, C1-4 alkyl or aryl; and R6, R7 and R8 which may be same or different are C1-4 alkyl, optionally substituted phenyl or a carrier in which the compound of formula I is reacted with a Lewis acid followed by reaction with water forming a hydroxy compound of the general formula II R1-OH II; A method for preparing a compound of the general formula III R1-O-A III in which R1 is the non-hydroxy moiety of a hydroxy compound; and A is an acyl group; A compound of the general formula IV R1-O-X IV in which R1 is the non-hydroxy moiety of a hydroxy compound; and X is a residue of a Lewis acid; A method according to claim 4 in which R1 is the non-hydroxy moiety of a hydroxy-containing amino acid forming part of a peptide, and one of R6, R7 and R8 is a carrier; and A compound of the general formula Ia <CHEM> wherein R1 is a carbohydrate moiety containing two or more sugar units or a derivative thereof.</p> |
