发明名称 Purification method for tumor necrosis factor
摘要 An improved method for purifying TNF, especially recombinantly produced TNF in bacteria, is disclosed. The purification employs a hydrophobic support in a chromatographic column which is then developed, preferably by HPLC. Preliminary purifications using anion exchange resins are also helpful.
申请公布号 US4677197(A) 申请公布日期 1987.06.30
申请号 US19850792815 申请日期 1985.10.30
申请人 CETUS CORPORATION 发明人 LIN, LEO S.;YAMAMOTO, RALPH
分类号 C12P21/00;A61K35/74;A61K38/00;C07K1/16;C07K1/36;C07K14/00;C07K14/52;C07K14/525;C12P21/02;(IPC1-7):C07K3/20 主分类号 C12P21/00
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