发明名称 |
Purification method for tumor necrosis factor |
摘要 |
An improved method for purifying TNF, especially recombinantly produced TNF in bacteria, is disclosed. The purification employs a hydrophobic support in a chromatographic column which is then developed, preferably by HPLC. Preliminary purifications using anion exchange resins are also helpful.
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申请公布号 |
US4677197(A) |
申请公布日期 |
1987.06.30 |
申请号 |
US19850792815 |
申请日期 |
1985.10.30 |
申请人 |
CETUS CORPORATION |
发明人 |
LIN, LEO S.;YAMAMOTO, RALPH |
分类号 |
C12P21/00;A61K35/74;A61K38/00;C07K1/16;C07K1/36;C07K14/00;C07K14/52;C07K14/525;C12P21/02;(IPC1-7):C07K3/20 |
主分类号 |
C12P21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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