| 摘要 |
1,210,489. Cephalosporin compounds. ELI LILLY & CO. 24 April, 1969 [25 April, 1968], No. 21075/69. Heading C2A. Novel 7 - [2<SP>1</SP> - (4<SP>11</SP> - nitrophenyl)acetamido] desacetoxycephalosporanic acid or pharmaceutically acceptable salts thereof, having the Formula (I) wherein M is H or a cation, is prepared by acylating 7-aminodesacetoxy cephalosporanic acid or a salt thereof with an acylating agent containing 4-nitrophenylacetyl groups, e.g. 4- nitrophenylacetic acid in the presence of a carbodiimide condensing agent, or the acid halide or anhydride of 4-nitrophenylacetic acid or mixed anhydride of 4-nitrophenylacetic acid with 4-nitrobenzoic acid. |
