摘要 |
1366667 Substituted bicyclic compounds F HOFFMANN-LA ROCHE & CO AG 25 Aug 1971 [26 Aug 1970] 3136/73 Divided out of 1366665 Heading C2C Novel compounds of formula where R<SP>1</SP> is primary alkyl with 1-5 carbon atoms, Z is carbonyl or a group of formula R<SP>7</SP> is H, lower acyl, lower alkyl, aryl lower alkyl, or tetrahydropyran-2-yl, R<SP>8</SP> is H or lower aliphatic hydrocarbyl, and m is 1 or 2, may be prepared by oxidation of a compound (II) of formula where R<SP>2</SP> is H, lower primary alkyl, or acyl. Compound II is prepared as described in Specification 1,366,664. The products may be optically active. |