摘要 |
NEW MATERIAL:cis-Dichloro-trans-dihydroxy(2-aminomethylaziridine)platinum (IV). USE:An antitumor agent having low toxicity and high water solubility. PREPARATION:For example, platinum (II) potassium chloride is reacted with 2-aminomethylaziridine in an aqueous solvent to give cisdichloro(2- aminomethylaziridine)platinum (II), which is reacted with hydrogen oxide to give a compound shown by the formula I.
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