发明名称 3-[methyl or dimethyl)amino]-6-(pyridinyl)pyridazines and their cardiotonic use
摘要 3-(NB)-4-Q-6-PY-pyridazines (I) or salts thereof, which are useful as cardiotonics, are prepared by reacting a 3-halo-4-Q-6-PY-pyridazine with an amine, H-NB, to produce I, where PY is 4- or 3-pyridinyl or 4- or 3-pyridinyl having one or two lower-alkyl substituents and Q is cyano when NB is NHCH3 or N(CH3)2, or Q is carbamyl when NB is NHCH3, or Q is hydrogen when NB is N(CH3)2. Cardiotonic use of said 3-(NB)-4-Q-6-PY-pyridazines or salts is shown.
申请公布号 US4590194(A) 申请公布日期 1986.05.20
申请号 US19810308413 申请日期 1981.10.05
申请人 STERLING DRUG INC. 发明人 LESHER, GEORGE Y.;DICKINSON, WILLIAM B.
分类号 C07D401/04;(IPC1-7):A61K31/44;C07D213/84;C07D213/74 主分类号 C07D401/04
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