摘要 |
3-(NB)-4-Q-6-PY-pyridazines (I) or salts thereof, which are useful as cardiotonics, are prepared by reacting a 3-halo-4-Q-6-PY-pyridazine with an amine, H-NB, to produce I, where PY is 4- or 3-pyridinyl or 4- or 3-pyridinyl having one or two lower-alkyl substituents and Q is cyano when NB is NHCH3 or N(CH3)2, or Q is carbamyl when NB is NHCH3, or Q is hydrogen when NB is N(CH3)2. Cardiotonic use of said 3-(NB)-4-Q-6-PY-pyridazines or salts is shown.
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