发明名称 |
Restriction endonuclease deletion mutants of vibrio cholerae - useful as avirulent strains for conferring protection against cholera |
摘要 |
<p>Culture of Vibrio cholerae comprising a V. cholerae strain having a restriction endonuclease DNA fragment deleted. The strain is then avirulent, while it retains capacity to colonise the intestine of a host animal.</p> |
申请公布号 |
ES8603952(A1) |
申请公布日期 |
1986.05.16 |
申请号 |
ES19490005302 |
申请日期 |
1984.03.02 |
申请人 |
UNIVERSITY OF MARYLAND AT BALTIMORE |
发明人 |
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分类号 |
C12N15/09;A61K;A61K39/106;A61K39/187;C07H21/04;C12N;C12N1/20;C12N1/21;C12N15/00;C12N15/65;C12N15/74;C12R;C12R1/63;(IPC1-7):C12N15/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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