发明名称 METHOD FOR PREPARING 3, 4- DIHYDRO- 2H- 1, 2- BENZOTHIAZIN- 3- CARBOXAMIDE- 1, 1- DIOXIDE
摘要 A novel compound of empirical formula C9H7N2O5SRR<1>Z (I) produced by reacting an ester of the formula <CHEM> with an equimolar amount of an amine of the formula ZNH2 in a reaction inert organic solvent at a temperature of from about 0 to 110 DEG C wherein R is hydrogen benzyl or (C1-C3) alkyl; R<1> is benzyl or (C1-C4) alkyl and Z is benzopyronyl, alkyl substituted benzopyronyl, 2-pyridyl, alkyl substituted-2-pyridyl, 2-thiazolyl, 2-thiazolyl substituted by one or two alkyl group, or 5-alkyl-3-isoxazolyl, each alkyl having from one to four carbon atoms; and a novel process utilizing the compounds of formula (I) as intermediates for production of known anti-inflammatory agents of the formula <CHEM> u
申请公布号 BG39296(A3) 申请公布日期 1986.05.15
申请号 BG19820057522 申请日期 1982.07.23
申请人 PFIZER INC 发明人 KARDYS,JOSEPH A.
分类号 C07D417/12;A61K;A61K31/54;C07C;C07D;C07D213/73;C07D261/14;C07D277/20;C07D277/40;C07D279/02;C07D513/22;C07G99/00 主分类号 C07D417/12
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