Thieno and furo¬2,3-c pyrrole derivatives, process for their preparation and medicaments containing them

摘要

Derivatives represented by the formula <IMAGE> in which X1 and X2 denote an oxygen or sulphur atom; R1 denotes a linear or branched alkyl radical containing from 1 to 8 carbon atoms, an alkynyl radical, an alkoxyalkyl radical containing from 3 to 8 carbon atoms or an aromatic residue; R2 denotes a hydrogen atom or a linear or branched alkyl radical; m = 2 or 3, when m = 2, X1 and X2 denote a sulphur atom. U denotes a 3,4-diaminocyclobuten-1,2-dione or aminosulphonylformamidine residue; U may also denote the nitrogenous structures <IMAGE> in which V denotes a nitrogen atom or a CH fragment; W denotes NO2 or CN; R3 denotes a hydrogen atom, a linear or branched alkyl radical containing 1 to 8 carbon atoms, or an alkynyl radical; R4 denotes an alkyl group containing from 1 to 3 carbon atoms. Medication with antagonist action on H2 receptors of histamine and antiulcer action, containing a thieno- or furo[2,3-c]pyrrole as active principle.