| 发明名称 |
5 ASA DRUG DELIVERY SYSTEM |
| 摘要 |
<p>The present invention relates to novel compounds for the prophylaxis and treatment of Inflammatory Bowel disease (IBD) via the administration of an effective amount in a suitable pharmaceutical dosage of a polymeric agent for releasing 5,5'-azobis-salicylic acid which comprises a non-degradable anionic exchange resin and the dianionic form of 5,5'-azobis-salicylic acid. The 5,5'-azobis-salicylic acid undergoes bacterial cleavage in the mammalian lower bowel to release 5-aminosalicylic acid.</p> |
| 申请公布号 |
CA1200204(A) |
申请公布日期 |
1986.02.04 |
| 申请号 |
CA19820404608 |
申请日期 |
1982.06.07 |
| 申请人 |
PHARMACIA AB |
发明人 |
PITZELE, BARNETT S.;JONES, PETER H. |
| 分类号 |
A61K31/785;A61K47/48;A61P1/04;C07C245/08;(IPC1-7):A61K31/665;A61K31/74 |
主分类号 |
A61K31/785 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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