摘要 |
<p>Beta-lactam cpds. of partial formula (I) are new: where n = 1 or 2. Pref. (I) are penicillin or cephalosporin derivs. of formula (Ia) or their salts: R1 = H, acyl (pref. of an antibacterially active penicillin or cephalosporin) or amino-protecting gp.; R2 = H or easily removable protecting gp.; Y = gp. of formula (a)-(d): n = 1 (prefd.) or 2; Z = H, halogen, 1-4C alkoxy, -CH2Q or -CH=CH-Q: Q = H, halogen, OH, SH, CN, COOH, carboxylic ester, carbamoyloxy, 1-4C alkoxy, acyloxy, C- or N- bonded heterocyclic gp. or heterocyclylthio.</p> |