| 摘要 |
NEW MATERIAL:Inclusion crystal comprising alpha-L-aspartyl-L-phenylalanine methyl ester: beta-cyclodextrin: crystal water=1:1:6 (molar ratio). When it is measured by powder X-ray diffractiometry using Cu-Kalpha ray, diffraction peak is shown at 7.2 deg., 10.2 deg., 11.9 deg., 17.8 deg. and 18.3 deg. diffraction angles (2theta), and Raman spectrum is shown at 830cm<-1> and 1,210cm<-1>. USE:A sweetener. Dissolution speed about three times as high as that of existing sweetener, and load for dissolution operation is extremely reduced. PREPARATION:alpha-L-Aspartyl-L-phenylalanine methyl ester and beta-cyclodextrin in a molar ratio of 0.5:1-1.5:1 are dissolved in water at 60 deg.C, allowed to stand at room temperature for 24hr, sealed with a stopper, allowed to stand at 4 deg.C precipitated crystal is filtered off after about 30 days, to give the above-mentioned novel substance. |
