Muconic acid productivity by a stabilized mutant microorganism population

摘要

This invention provides an improved fermentation process for bioconversion of toluene to muconic acid. The process involves operating the bioconversion system under phosphate-limiting conditions so as to achieve an increase in specific muconic acid productivity with a stabilized population of microorganism such as an ATCC No. 31,916 type of Pseudomonas putida Biotype A mutant strain.