Diagnostic antigen for swine pseudorabies disease virus carriers.

摘要

A diagnostic antigenic factor for determining swine carriers of pseudorabies is obtained from the culture medium in which the pseudorabies (PR) virus is cultured, the medium being removed at an intermediate time in the PR virus replication cycle. The antigenic factor thus obtained can be used as a complementary antigen with reference to the lectin-bound glycoprotein antigens of PR virus from which immunizing sub-unit vaccines can be prepared. Therefore, sub-unit vaccinated swine which are non-carriers of PR virus can be distinguished from carriers. This result can provide an important tool for control of swine pseudorabies and its eventual eradication.