| 摘要 |
<p>Novel substituted beta -carboline derivatives of Formula I <IMAGE> (I) wherein R3 is an oxadiazolyl residue of the formula <IMAGE> wherein R5 stands for lower alkyl of up to 3 carbon atoms or an ester <IMAGE> with R6 being hydrogen or lower alkyl of up to 3 carbon atoms, R4 is hydrogen, lower alkyl of up to 3 carbon atoms, or CH2OR9 wherein R9 is lower alkyl of up to 3 carbon atoms, RA is phenyl or a hydrocarbon residue containing 2-10 carbon atoms which can be cyclic or acyclic, saturated or unsaturated, branched or unbranched, and which can optionally be substituted by oxo, formyl OH, O-alkyl of up to 3 carbon atoms or phenyl, and wherein, in a cyclic hydrocarbon residue, a CH2-group can be replaced by oxygen, exhibit an effect on the central nervous system and thus are suitable as psychopharmaceuticals.</p> |
