| 摘要 |
Pyranones [I; R1 = H, COOR5, CONHR5, cyano, 5-tetrazolyl or 5- tetrazolylamino carbonyl; R5 = H or C1-6 alkyl; R3 = R6=(Z)m; m = 0 or 1; Z = O, S, SO2, or CO; R6 = halogen, C1-4 alkyl or C3-6 cycloalkyl substituted phenyl useful in acute hypersensitivity, were prepd. by the reaction of II and acids. Thus, 8.2 g 1- (4methoxyphenyl)-2-propanone was reacted with 9.5 ml dimethylformamidedimethyl at 95-100≦̸C and crystallized with ether- petroleum spirit to give 4-dimethylamino-3-(4-methoxyphenyl)-3butene- 2-one.
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