发明名称 1-FENOXI-3-HYDROXIINDOLYLALKYLAMINO-3-PROPANOLER, FORFARANDE FOR FRAMSTELLNING DERAV OCH FARMACEUTISKA KOMPOSITIONER INNEHALLANDE DESAMMA
摘要 1-(2-Cyanophenyloxy)-3-(hydroxyindolylalkylamino)-2-propanols and their salts are cardiovascular agents having promise as antihypertensive agents by virtue of their vasodilating and adrenergic receptor blocking actions. Preferred compounds contain the 3-indolyl-tertiary-butylamino moiety. The compounds have the formula <IMAGE> wherein one of R<1> and R<2> is hydrogen and the other is hydrogen or C1-4 alkyl; R<3> and R<4> are independently selected from hydrogen or C1-4 alkyl; R<5> is halogen, hydrogen, hydroxy, or C1-4 alkyl;o
申请公布号 SE8403112(L) 申请公布日期 1984.12.11
申请号 SE19840003112 申请日期 1984.06.08
申请人 BRISTOL MYERS CO 发明人 KREIGHBAUM W E
分类号 C07D209/10;A61K31/275;A61K31/40;A61K31/403;A61K31/404;A61P9/08;A61P9/12;A61P25/02;C07D209/14;C07D303/22;(IPC1-7):C07D209/14 主分类号 C07D209/10
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