摘要 |
The present invention relates to a cell expressing an amino acid-N-acyl-transferase, which is preferably recombinant, and an acyl-CoA synthetase, which is preferably recombinant, wherein the cell has a reduced fatty acid degradation capacity, a method for producing acyl amino acids, comprising the step contacting an amino acid and an acyl CoA in the presence of an amino acid-N-acyl-transferase, which is preferably isolated and/or recombinant, wherein the amino acid-N-acyl-transferase is preferably a human amino acid-N-acyl-transferase, or culturing the cell and a reaction mixture comprising an amino acid-N-acyl-transferase, which is preferably isolated and/or recombinant, an acyl-CoA synthetase, which is preferably isolated and/or recombinant, an amino acid and either a fatty acid-CoA or a fatty acid and an acyl-CoA-synthase. |
申请人 |
EVONIK DEGUSSA GMBH |
发明人 |
GRAMMANN, KATRIN;WOLTER, JAN;SCHAFFER, STEFFEN;CORTHALS, JASMIN;HAAS, THOMAS;POTGRAVE, NICOLE;REINECKE, LIV;OLFERT, MAIK |