| 摘要 |
<p>This invention provides a compound of the formula (I) in which Ar1 and Ar2, which may be the same or different, each represents a phenyl radical, unsubstituted or substituted by one or more of the same or different substituents selected from a halogen atoms, alkyl radicals containing 1 to 4 carbon atoms, alkoxy radicals containing 1 to 4 carbon atoms and dialkylamino radicals containing 2 to 6 carbon atoms; provided that both of the substituents represented by Ar1 and Ar2 are not unsubstituted phenyl groups, R1 represents a hydrogen atom or an alkyl radical having 1 to 4 carbon atoms, n represents 0, 1 or 2, and Z represents an alkyl radical having 1 to 6 carbon atoms having additionally one or two of the same or different functional groups selected from hydroxy groups, alkoxy radicals containing 1 to 4 carbon atoms, alkylenedioxy radicals containing 2 to 4 carbon atoms, acyloxy radicals containing 1 to 4 carbon atoms, and alkoxycarbonyl radicals containing 2 to 5 carbon atoms, alkenyl containing 2 to 4 carbon atoms which may be substituted with hydroxy; or alkynyl containing 2 to 4 carbon atoms and which may be substituted with hydroxy, there being no more than one alkoxycarbonyl radical present and the total number of carbon atoms in Z being at least 2, or a pharmaceutically acceptable salt thereof. These compounds have anti-inflammatory and antiallergic activity.</p> |
