发明名称 |
ANTIBIOTIC A-4696 FACTORS B.SUB.1, B.SUB.2, B.SUB.3, C IN1A XX, C.SUB.3, AND E IN1 XX |
摘要 |
Antibiotic A-4696 factors B1, B2, B3, C1a, C3, and El are isolated from antibiotic A-4696, the latter being produced by Actinoplanes missouriensis strains ATCC 31680, ATCC 31682, or ATCC 31683 under submerged aerobic conditions in a culture medium and isolated from the fermentation broth by absorption on an ion exchange resin and eluted therefrom at pH 10.5 with sodium hydroxide. The novel factors are separated by thin layer chromatography and high pressure liquid chromatography and have antimicrobial and growth promotant activity. |
申请公布号 |
CA1171008(A) |
申请公布日期 |
1984.07.17 |
申请号 |
CA19810391804 |
申请日期 |
1981.12.09 |
申请人 |
LILLY (ELI) AND COMPANY |
发明人 |
DEBONO, MANUEL;MERKEL, KURT E.;WEEKS, ROBERT E.;COLE, HERALD J. |
分类号 |
C07D498/22;A23K20/195;A61K38/00;C07K9/00;C12P1/06;C12P17/18;C12R1/045 |
主分类号 |
C07D498/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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