发明名称 PROCESS FOR PRODUCING NEW 2-SUBSTITUTED AND 2,6-DISUBSTITUTED PENEM COMPOUNDS
摘要 This invention relates to phosphorane compounds of the formula wherein Y is hydrogen, ethyl or hydroxyethyl, Q is phenyl or (lower) alkyl, R" is an easily removable ester group and X represents certain organic substituents. Also included in the invention are pharmaceutically acceptable salts of the above compounds and derivatives of the above compounds in which the carboxyl group at the 3- position is protected by an easily removable ester protecting group. The compounds of the present invention are of use as intermediates in the preparation of penem compounds having potent antibacterial activity.
申请公布号 YU215382(A) 申请公布日期 1983.06.30
申请号 YU19820002153 申请日期 1982.09.27
申请人 BRISTOL MYERS CO 发明人 MENARD M.
分类号 A61K31/425;A61K31/12;A61K31/397;A61K31/43;A61P31/04;C07D205/08;C07D205/09;C07D209/48;C07D499/00;C07D499/04;C07D499/06;C07D499/88;C07D499/897;C07F7/08;C07F7/10;C07F7/18;C07F9/535;C07F9/568;C07F9/6539;C07F9/6541;C07F9/6558;C07F9/6561;(IPC1-7):C07D499/00 主分类号 A61K31/425
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