| 摘要 |
NEW MATERIAL:Y-T 0678H substance (6-hydroxy-3-oxo-1,2-benzisooxazoline) shown by the formula; appearance: slightly yellow white powder; melting point: 247 deg.C(decomposition point); specific rotatory power:[alpha]D<26> 0 deg. (C 0.5 MeOH); values of elemental analysis: calcd. for C7H5NO3, C:55.64, H:3.33, N:9.27, O:31.76 found C:55.38, H:3.21, N:9.06(%); color reaction: positive in ferric chloride, negative in ninhydrin; an acidic substance; solubility; easily soluble in methanol, etc., slightly soluble in water or ethyl acetate, insoluble in benzene, etc. USE:An antibiotic. Having improved effect on Gram-negative bacteria. PROCESS:Chromobacterium. sp. Y-T 0678H strain (FERM P-6144) capable of producing Y-T 0678H substance is cultivated, to give a compound shown by the formulaI. |
