摘要 |
<p>Piperidine derivatives of the general formula: wherein R represents a hydrogen atom, or a (C1-4)alkyl hydroxy(C1-4)alkyl, or (C1-4)alkoxycarbonyl radical or a benzyl radical optionally carrying a substituent selected from halogen atoms and (C1-4)alkoxy radicals or the phenethyl radical, or the 3-phenylpropyl radical, and X represents one or more hydrogen or halogen atoms or (C1-4)alkyl, (C1-4)alkoxy, trifluoromethyl or methylenedioxy radicals, or alternatively X forms with the phenyl nucleus a naphthyl radical, with the proviso that when R represents a hydrogen atom X is other than a hydrogen atom, are new compounds useful as medicaments and, more particularly, as antidepressants. They may be prepared by reaction of a 4-hydroxypiperidine with a benzyl halide.</p> |