发明名称 (B1) ;METHOD OF OBTAINING NOVEL SUBSTITUTED DERIVATIVES OF PHENOXYAMIONOPROPANOL
摘要 Substituted phenoxy-aminopropanols of the formula <IMAGE> I wherein R is a branched-chain alkyl of 3 or 4 carbon atoms, R1 is hydrogen, halogen or lower alkyl and R2 and R3, independently, are hydrogen, halogen, lower alkyl, lower alkoxy or lower alkylthio, and pharmaceutically acceptable acid addition salts thereof, are described. A process for their preparation, as well as pharmaceutical preparations containing them are also described. The compounds of formula I and their salts possess cardioselective beta -adrenergic blocking activity and antihypertensive activity.
申请公布号 PL231453(A1) 申请公布日期 1982.08.02
申请号 PL19810231453 申请日期 1981.06.02
申请人 HOFFMANN LA ROCHE 发明人
分类号 C07C217/34;A61K31/135;A61K31/138;A61P9/00;A61P9/06;A61P9/12;C07C29/147;C07C43/178;C07C43/20;C07C43/23;C07C45/71;C07C49/84;C07C59/66;C07C215/00;C07C215/02;C07D303/24;(IPC1-7):07C/ 主分类号 C07C217/34
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