发明名称 AROMATIC AMINOETANOL COMPOUNDS, PROCESS FOR PRODUCTION THEREOF, AND UTILIZATION THEREOF
摘要 The invention provides compounds of the formula …<CHEM>… wherein A represents a direct bond or the group -O-CH2-, B represents a C1-C11 alkylene group bonded to a carbon atom of the aromatic ring D either directly or through -O-, -S-, -SO- or -NH-,… W represents a carbon or nitrogen atom, R1 represents a C1-C7 alkyl group, a hydroxy-C1-C6 alkyl group, or a phenyl- or diphenyl- alkyl group with the alkyl group having 1 to 4 carbon atoms,… R2 represents hydrogen, halogen, OH, C1-C4 alkyl, NO2, C1-C4 alkoxy, acetyl, allyloxy, carbamoyl or sulfamoyl, and when two or more R2 groups exist, they may be idential or different, and… n represents 1, 2 or 3 and m represents 1 or 2, provided that n + m >/= 4;… and acid addition salts thereof; processes for producing them; and pharmaceutical compositions comprising them for use in the treatment of diseases of the cardiovascular system.
申请公布号 ZA8100932(B) 申请公布日期 1982.03.31
申请号 ZA19810000932 申请日期 1981.02.12
申请人 KOWA CO LTD 发明人 HIROMICHI SHIGYO;YOSHINORI KYOTANI;MASAHIKO NAGAKURA;MASAMI SHIRATSUCHI;NAOTOSHI SAWADA;NOBORU SHIMIZU;HISASHI KUNIEDA;KIYOSHI KAWAMURA;SEIICHI SATO;YASUMI UCHIDA;TOSHIHIRO AKASHI
分类号 A61K31/21;A61K31/135;A61K31/165;A61K31/44;A61K31/4402;A61K31/4418;A61P9/00;A61P9/12;A61P25/02;A61P25/28;C07C67/00;C07C203/04;C07C213/00;C07C217/32;C07C217/70;C07C219/16;C07C219/34;C07C225/16;C07C231/00;C07C231/12;C07C235/42;C07C235/46;C07C237/30;C07C301/00;C07C303/40;C07C311/17;C07C311/29;C07C313/00;C07C315/04;C07C317/22;C07C317/24;C07C317/32;C07C319/20;C07C323/25;C07D213/30;C07D213/60;C07D213/64;C07D213/69;C07D303/24;C07D303/26;C07D309/12 主分类号 A61K31/21
代理机构 代理人
主权项
地址