发明名称 |
Process for preparing optically active tryptophanes. |
摘要 |
Biochemical optical resolution of DL-tryptophanes in which DL-tryptophane amides are interacted with the culture products, or their treated products, of a microorganism capable of producing amidase is described. L-tryptophane amides in racemic DL-tryptophane amides are asymmetrically hydrolyzed to form optically active L-tryptophanes at a high yield and almost all D-tryptophane amides remain without being subjected to hydrolysis. The resultant D-tryptophane amides are readily hydrolyzed, after separating L-tryptophanes, to form optically active D-tryptophanes at a high yield. |
申请公布号 |
EP0043211(A2) |
申请公布日期 |
1982.01.06 |
申请号 |
EP19810302751 |
申请日期 |
1981.06.18 |
申请人 |
UBE INDUSTRIES, LTD. |
发明人 |
NAKAI, MAMORU;OHSHIMA, TOKIO;KIMURA, TOMIO;OMATA, TETSUO;IWAMOTO, NORITADA |
分类号 |
C12N9/80;C12P13/04;C12P13/22;C12P41/00;C12R1/025;C12R1/05;C12R1/06;C12R1/07;C12R1/13;C12R1/145;C12R1/20;C12R1/225;C12R1/265;C12R1/32;C12R1/365;C12R1/38;C12R1/46;C12R1/465;C12R1/645;C12R1/65;C12R1/66;C12R1/72;C12R1/77;C12R1/78;C12R1/80;C12R1/84;C12R1/845;C12R1/85;C12R1/88;C12R1/885 |
主分类号 |
C12N9/80 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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