6-Substituted 4-(2',3'-dichlorophenyl)-2-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid diesters having hypotensive properties as well as process for their preparation and pharmaceutical preparations containing same.

摘要

The present invention relates to new compounds having anti-hypertensive effect, which compounds are of the formula I, <CHEM> wherein R<1> is selected from the group consisting of -CH3, -CH2CH2OCH3, and -CH(CH3)CH2OCH3, R<2> is selected from the group consisting of -CH3, -C2H5, -CH2CH2OCH3, and -CH(CH3)CH2OCH3, whereby when R<1> is -CH3, R<2> is -CH3, -C2H5, -CH2CH2OCH3, or -CH(CH3)CH2OCH3, when R<1> is -CH2CH2OCH3, R<2> is -CH2CH2OCH3, or -CH(CH3)CH2OCH3, and when R<1> is -CH(CH3)CH2OCH3, R<2> is -CH(CH3)CH2OCH3, and R<3> is selected from the group consisting of alkyl with 2 to 3 C, alkoxyalkyl with 2 to 3 C, and alkoxyalkoxyalkyl with 3 to 5 C, process for the preparation of said compounds, pharmaceutical preparations containing said compounds.