发明名称 |
KINOLINKARBOXYLSYRADERIVAT OCH SETT FOR FRAMSTELLNING DERAV |
摘要 |
Certain novel quinoline carboxylic acid derivatives, being the compounds of the general formula: <IMAGE> (wherein R2 is halogen; R3 is a 1- piperazinyl or 4-(C1-C5)alkyl- piperazinyl; and either R1 is (C1-C5) alkyl and R4 is halogen or (C1-C5) alkyl, or R1 and R4 are each alkylene and together form a 5 or 6 membered ring which may be substituted by a (C1-C5) alkyl radical) and the hydrates and salts thereof, possess good anti-bacterial activity against both gram-negative and gram-positive bacteria. They may be prepared by reacting a corresponding 7-halo quinoline carboxylic acid derivative with a compound of formula R3H. The 7-halo quinoline carboxylic acid derivatives employed as starting materials are novel compounds which may be prepared by processes analogous to known processes. |
申请公布号 |
SE8005534(L) |
申请公布日期 |
1981.02.23 |
申请号 |
SE19800005534 |
申请日期 |
1980.08.04 |
申请人 |
KYORIN SEIYAKU KK |
发明人 |
IRIKURA T;KOGA H;MURAYAMA S |
分类号 |
C07D215/06;A61K31/47;A61K31/4709;A61P31/04;C07D215/18;C07D215/22;C07D215/233;C07D215/56;C07D401/04;C07D455/04;(IPC1-7):C07D401/04 |
主分类号 |
C07D215/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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