| 摘要 |
<p>A antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces with out substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl puridinium chloride, are typical examples of antibacterial agents. The antistain additive is a quaternary aminoalkylene phosphonic acid, such as N-methyl amiontri(methylene phosphonic acid) and salts thereof, a diphosphono pyrollidone, an N-methylene phosphonic acid and salts thereof, a phosphonoacetic acid and salts thereof or a phosphono-containg compound of the formula where R1 is hydrogen, C1-C4 alkyl or (CH2)1-2 COOH and R2 is PO3H2, , or .</p> |
