发明名称 Novel nitrosourea compounds and process for preparing the same
摘要 A compound of the formula: <IMAGE> wherein R1 is lower alkoxy, lower alkoxy-methoxy or 2-hydroxy-ethoxy, R2 is aldo-pentofuranosyl, aldo-pentopyranosyl, aldohexopyranosyl or O-aldo-hexopyranosyl-(1->4)-aldo-hexopyranosyl, and A is straight or branched alkylene of one to four carbon atoms, said alkylene being substituted with from 0 to at least one lower alkoxy group, is disclosed. A new intermediate used in the preparation of this compound is also disclosed. The end products are useful for inhibiting the growth of malignant tumor cells in warm-blooded animals; especially Leukemia and Ejrlich ascites carcinoma. Effectiveness on human beings has not yet been demonstrated.
申请公布号 US4241053(A) 申请公布日期 1980.12.23
申请号 US19790066421 申请日期 1979.08.14
申请人 TANABE SEIYAKU CO LTD 发明人 ARAI, YOSHIHISA;OZEKI, MASAKATSU;TSUJIHARA, KENJI
分类号 C07H13/12;(IPC1-7):A61K31/70;A61K31/73 主分类号 C07H13/12
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