发明名称 |
Dibenz[b,f]oxepin and dibenzo[b,f]thiepin derivatives, process for preparation thereof, method of using the same, and compositions thereof |
摘要 |
Novel dibenz[b,f]oxepin and dibenzo[b,f]thiepin derivatives of the formula <IMAGE> wherein X is an oxygen or sulfur atom, each of R1 and R2 is a hydrogen atom or a methyl group, and R3 is a hydrogen atom or a 2-(2-hydroxyethoxy)ethyl group; provided that when R1 is a hydrogen atom, the group <IMAGE> is a group other than a 1-carboxyethyl group; and when X is a sulfur atom, both R1 and R2 are methyl groups; and pharmaceutically acceptable salts of said compounds in which R3 is a hydrogen atom. Compositions of said compounds, processes for the preparation of said compounds, and a method of using said compounds are also provided. These novel compounds have excellent anti-inflammatory, analgesic and antipyretic activities.
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申请公布号 |
US4238620(A) |
申请公布日期 |
1980.12.09 |
申请号 |
US19790013477 |
申请日期 |
1979.02.21 |
申请人 |
DAINIPPON PHARMACEUTICAL CO LTD |
发明人 |
NAGAI, YASUTAKA;NAKAMURA, HIDEO;UNO, HITOSHI |
分类号 |
A61K31/335;A61P25/04;A61P29/00;C07C41/26;C07C43/295;C07C59/68;C07C65/34;C07D295/194;C07D313/14;C07D337/14;(IPC1-7):07D313/14;07D337/14 |
主分类号 |
A61K31/335 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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